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DTSTART;TZID=Asia/Kolkata:20230806T134000
DTEND;TZID=Asia/Kolkata:20230906T144500
DTSTAMP:20230830T234036Z
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LAST-MODIFIED:20230830T234036Z
UID:47366-1691329200-1694011500@www.ashoka.edu.in
SUMMARY:First Lecture in Ashoka History Monsoon Seminar 2023
DESCRIPTION:ABSTRACT \nWriting a history of the region of Northeast India is fraught with difficulties – difficulties presented not only by a lack of sources\, but also by differences in scale – of time\, geography\, and culture within the region. The abrupt ruptures caused by political boundaries do not help either. Considering the region as an ecological zone having its own distinctive habitat may\, I suggest\, facilitate as well as provide pointers for the writing of the history of the region. The ecological zone of which the region is a part gives the region its coherence and unity\, and studying the entanglements between humans and non-humans that are specific to the region is an interesting way to show how these interactions have formed the people of the region. Close\, long-lasting relationships with animals characterise most groups in the region not only in practical\, and instrumental terms but also in symbolic and emotional terms. The paper will explore the ways in which the lifeworlds of the people of the region are bound together by these relations. Secondly\, an understanding of human-more-than-human interactions enable us to see the spatial dimensions or the creation of specific cultural geographies. Going beyond the binaries of forest people v/s settled agriculturists\, slash and burn v/s settled agriculture\, primitive v/s civilized the paper will explore how the interplay of micro-organisms\, animals and plants created spatial patterns that changed over time with human and nonhuman mobilities. \n  \nJoy LK Pachuau is Professor of History at the Centre for Historical Studies\, Jawaharlal Nehru University\, New Delhi\, India. More recently she has been working on the history of Northeast India with a focus in the history of identity formations. She is also interested in the visual history of the region. Dr. Pachuau’s publications include Being Mizo: Identity and Belonging in Northeast India\, (OUP\, 2014)\, The Camera as Witness: A Social History of Mizoram\, Northeast India (with Willem van Schendel\, CUP\, 2015)\,  Christianity in Indian History: Issues of Culture\, Power and Knowledge (eds with P. Malekandathil and Tanika Sarkar\, Primus 2016) and Landscape\, Culture and Belonging: Writing the History of Northeast India\, New Delhi (edited with Neeladri Bhattacharya: Cambridge University Press\, 2019). Her most recent book\, Entangled Lives: Human-Animal-Plant Histories of the Eastern Himalayan Triangle\, co-written with Willem van Schendel\, was published in 2022 from Cambridge University Press.
URL:https://www.ashoka.edu.in/event/first-lecture-in-ashoka-history-monsoon-seminar-2023/
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DTSTART;TZID=Asia/Kolkata:20230807T110000
DTEND;TZID=Asia/Kolkata:20230807T120000
DTSTAMP:20230801T070004Z
CREATED:20230801T070004Z
LAST-MODIFIED:20230801T070004Z
UID:46122-1691406000-1691409600@www.ashoka.edu.in
SUMMARY:Mechanobiology of organ development and homeostasis
DESCRIPTION:Abstract: \nOrgan morphology is critical for its function. Mechanical signals and biochemical cues influence cell and tissue behavior to shape an organ during development. Although significant advances have been made in understanding the genetic regulation of 3D organ development\, the role of mechanical forces are not fully understood. I use Caenorhabditis elegans to decipher the mechanical basis of organ development – using gonad development as a model. The C. elegans gonad has two symmetrical U-shaped arms\, each with a single somatic cell called a Distal tip cell (DTC) at its tip. The DTC functions as a leader cell guiding follower germ cells to form the U-shaped architecture. Using live-imaging\, laser ablation\, DTC-specific genetic manipulation\, and a qualitative physical modeling\, I discovered that the gonad elongates not by the pulling force of the leader cell migration\, but rather due to a pushing force generated by proliferating germ cells confined behind the DTC. Local release of matrix-degrading metalloproteases by the DTC determines the direction of gonad elongation. Moreover\, asymmetric DTC-ECM adhesion creates torque that drives the U-turning of the gonad. Taken together\, this study provides novel mechanistic insight into organ morphogenesis which may also be relevant for other developmental systems as well as solid tumor metastasis. \n  \nAbout the speaker: \nDr. Priti Agarwal is a Research Fellow at Tel Aviv University\, Israel. She combines C. elegans genetics\, quantitative fluorescence microscopy\, and microfluidics to understand the mechanics of organ development. Priti has a Ph. D from IIT\, Kanpur and thereafter worked at the Mechanobiology Institute\, Singapore before moving to the Department of Cell and Developmental Biology at Tel-Aviv University.  \n 
URL:https://www.ashoka.edu.in/event/mechanobiology-of-organ-development-and-homeostasis/
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