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DTSTART:20220101T000000
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DTSTART;TZID=Asia/Kolkata:20230806T134000
DTEND;TZID=Asia/Kolkata:20230906T144500
DTSTAMP:20230830T234036Z
CREATED:20230830T234036Z
LAST-MODIFIED:20230830T234036Z
UID:47366-1691329200-1694011500@www.ashoka.edu.in
SUMMARY:First Lecture in Ashoka History Monsoon Seminar 2023
DESCRIPTION:ABSTRACT \nWriting a history of the region of Northeast India is fraught with difficulties – difficulties presented not only by a lack of sources\, but also by differences in scale – of time\, geography\, and culture within the region. The abrupt ruptures caused by political boundaries do not help either. Considering the region as an ecological zone having its own distinctive habitat may\, I suggest\, facilitate as well as provide pointers for the writing of the history of the region. The ecological zone of which the region is a part gives the region its coherence and unity\, and studying the entanglements between humans and non-humans that are specific to the region is an interesting way to show how these interactions have formed the people of the region. Close\, long-lasting relationships with animals characterise most groups in the region not only in practical\, and instrumental terms but also in symbolic and emotional terms. The paper will explore the ways in which the lifeworlds of the people of the region are bound together by these relations. Secondly\, an understanding of human-more-than-human interactions enable us to see the spatial dimensions or the creation of specific cultural geographies. Going beyond the binaries of forest people v/s settled agriculturists\, slash and burn v/s settled agriculture\, primitive v/s civilized the paper will explore how the interplay of micro-organisms\, animals and plants created spatial patterns that changed over time with human and nonhuman mobilities. \n  \nJoy LK Pachuau is Professor of History at the Centre for Historical Studies\, Jawaharlal Nehru University\, New Delhi\, India. More recently she has been working on the history of Northeast India with a focus in the history of identity formations. She is also interested in the visual history of the region. Dr. Pachuau’s publications include Being Mizo: Identity and Belonging in Northeast India\, (OUP\, 2014)\, The Camera as Witness: A Social History of Mizoram\, Northeast India (with Willem van Schendel\, CUP\, 2015)\,  Christianity in Indian History: Issues of Culture\, Power and Knowledge (eds with P. Malekandathil and Tanika Sarkar\, Primus 2016) and Landscape\, Culture and Belonging: Writing the History of Northeast India\, New Delhi (edited with Neeladri Bhattacharya: Cambridge University Press\, 2019). Her most recent book\, Entangled Lives: Human-Animal-Plant Histories of the Eastern Himalayan Triangle\, co-written with Willem van Schendel\, was published in 2022 from Cambridge University Press.
URL:https://www.ashoka.edu.in/event/first-lecture-in-ashoka-history-monsoon-seminar-2023/
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DTSTART;TZID=Asia/Kolkata:20230901T110000
DTEND;TZID=Asia/Kolkata:20230901T120000
DTSTAMP:20230824T024747Z
CREATED:20230824T024747Z
LAST-MODIFIED:20230824T024747Z
UID:46973-1693566000-1693569600@www.ashoka.edu.in
SUMMARY:Molecular and cellular profiling of Triple-Negative Breast Cancer in an Indian cohort
DESCRIPTION:Abstract: "Triple-negative breast cancer (TNBCs) is the most clinically aggressive breast cancer subtype presented with patients at an early age\, more regional metastasis and higher tumor grade and shows early recurrences and poor survival outcome. Poor understanding of this subtype and the lack of targeted therapy make it difficult to manage. A recent meta-analysis revealed that the incidence of TNBC in India is three times higher compared to reported Western cohorts. Therefore\, a better understanding of this disease and the factors promoting the disease progression and long-term survival is needed for an Indian cohort. To address this\, we look at an in-depth understanding of cellular and molecular profiles in breast cancer patients from a Pune Biobank (Busheri et al\, 2021). \nFFPE tissue samples derived from primary untreated tissue with known molecular subtypes\, lateral clinical\, pathological\, treatment and follow-up data were included in this study. The tumor microenvironment is a diverse milieu of stromal cells\, lymphocytes\, macrophages\, dendritic cells\, and tumor cells. Interactions among these cells affect the disease progression and patient outcomes. For cellular profiling\, we focus on tumor immune microenvironment (TIME)\, including total tumor-infiltrating lymphocytes (TILs) proportion\, the spatial distribution of TILs\, and cellular subtypes. Our analysis revealed a unique observation that TNBC patients had a higher proportion of patients with intra-tumoral TILs\, and is it is in fact has important clinical associations within our cohort. To identify the immune cell subtypes in TME\, we used cutting-edge technologies such as multiplexed immunohistochemistry and multispectral imaging and analysis. Complex TME milieu in relation to tumors in chemotherapy-treated patients will help us understand what drives the response within these patients. \nTo further our understanding of TNBC in India\, we focused on the molecular profile of TNBC with known therapeutic potential in other cancers\, EGFR and AR. These markers were used to prognosticate TNBC and identify a unique expression profile specific to India. In an attempt to truly take back our observations from the bench-to-bedside\, we propose a multi-centric phase 3 clinical trial based on our observation in this study."  \nAbout the speaker: Pooja is a Ph.D. scholar at Ashoka University and affiliated to CTCR\, Pune since 2018. She is currently working on her thesis project under the guidance of Prof LS Shashidhara and Dr Madhura Kulkarni. She obtained her master’s degree in biotechnology\, post which she was trained in Drosophila genetics\, using flies as a tumor model to identify putative tumor suppressor genes (TSGs). Moving to translational cancer field\, her focus has been in uncovering the unique clinical and molecular characteristics of Indian triple-negative breast cancers for better disease management. She strongly believes the fact that science cannot be pursued alone and that a solid teamwork and interdisciplinary approach is needed to tackle the current issues in cancer management. Outside lab\, she indulges in baking desserts with an elaborate recipe\, stretch her legs with recreational badminton and swimming\, travelling to serene mountains\, and spending time with her notorious house cat. \n 
URL:https://www.ashoka.edu.in/event/molecular-and-cellular-profiling-of-triplenegative-breast-cancer-in-an-indian-cohort/
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DTSTART;TZID=Asia/Kolkata:20230901T150000
DTEND;TZID=Asia/Kolkata:20230901T160000
DTSTAMP:20230825T053932Z
CREATED:20230825T053932Z
LAST-MODIFIED:20230825T053932Z
UID:47080-1693580400-1693584000@www.ashoka.edu.in
SUMMARY:Where insect communication and fish quantitative cognition meet
DESCRIPTION:Title: Where insect communication and fish quantitative cognition meet \nAbstract: A lot of people wonder where and how the different directions in our lab come together. We work on the neuroethology of insect communication on the one hand\, and fish quantitative and economic cognition on the other. Beyond the general common ground shared by these questions in the broader framework of cognition and behavioural ecology\, we explain the links between these specific lines of thought and the trajectory of the lab
URL:https://www.ashoka.edu.in/event/where-insect-communication-and-fish-quantitative-cognition-meet/
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