Biology Colloquium | Judith N. Mandl
September 28 @ 6:00 pm - 7:00 pm
Title: “Peering at the ecology of T cells through a cell migration lens“
Abstract: T cells, important effector cells of the immune system, are highly dynamic cells in both space and time. Their commute between and within tissues in the body is essential to effective immune responses. In my lab, we study how immune cell migratory processes orchestrate T cell responses, and the challenges that T cells face when they migrate within distinct tissue environments. We are particularly interested in explaining immune cell population heterogeneity in behaviour and function, and use a variety of methods to perturb immune cell migration in particular to learn from unexpected outcomes. Overall, our work on understanding the spatial ecology of T cells in diverse microanatomies aims to provide new tools to prevent T cells survival in specific tissues where they are causing disease (autoimmunity, allergies, transplantation), or to increase their mobility in challenging, crowded microenvironments such as tumours.
Please join via link below:
Meeting ID: 974 2807 7739
Speaker’s Bio: Dr. Mandl is the Co-director, Flow Cytometry Core Facility, Life Sciences Complex, McGill University, Canada.
She did her Bachelors in Computational Biology from the University of Warwick, the UK, followed by her Ph.D. from Emory University, USA. She got her Postdoctoral Training at the Laboratory of Systems Biology, National Institutes of Health (USA). Her Research Area is mainly focused on Immunology and Molecular & Cell Biology