Biology Seminar | Anindya Ganguly
January 21 @ 6:00 pm - 7:00 pm
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Title: Building a cell: How cells calibrate motor activity during cell wall morphogenesis
Speaker: Dr. Anindya Ganguly
University of Virginia, Charlottesville
Abstract: Construction of the plant cell wall demands coordinated deposition of cell wall construction materials like cellulose and matrix polysaccharides. My research shows that vesicles containing matrix polysaccharides are transported along the microtubules by a kinesin-4 motor into a growing cell wall. Interestingly, the same kinesin-4 motor also simultaneously works to stabilize the microtubule tracks to ensure harmonized delivery of the vesicles at the cell wall. Moreover, kinesin-4 remains highly abundant in growing cells in order to ensure rapid cell wall expansion. Conversely, kinesin-4 is rare in mature cells where cell wall growth has ceased. Intriguingly, the abundance of kinesin-4 motors required for the expansion of young growing cells is regulated by a unique mechanism that may well be conserved among the eukaryotes. Altogether, my research shows how an intricate network of multiple proteins delicately controls plant cell wall morphogenesis.