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Chemical Probes for ATPase Mechanoenzymes: Structural Basis for Activating an Enzyme that can

Dissolve Pathogenic Protein Aggregates and Induce autophagy

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About his lab:

Prof. Kapoor’s lab studies the molecular mechanisms required for accurate propagation of genetic material during cell division, with the goal of developing new therapies to treat cancer. Research in the lab has two areas of focus: discovering and developing new tools to probe protein function, and using them to dissect dynamic cellular processes such as cytoskeleton organization and cell division.

BIO:

Prof. Kapoor graduated with honors from the California Institute of Technology with bachelor’s degrees in chemistry and biology in 1993. He received his Ph.D. in chemistry in 1998 from Harvard University and did his postdoctoral research at Harvard Medical School. He came to Rockefeller in 2001 as assistant professor and was named associate professor in 2005 and professor in 2008.  

He received the 2012 Irving Sigal Young Investigator Award from The Protein Society and a Leukemia and Lymphoma Society Scholar Award in 2008. In 2003 he was named a Pew Fellow in the Biomedical Sciences. 

Prof. Kapoor is a faculty member in the David Rockefeller Graduate Program, the Tri-Institutional M.D.-Ph.D. Program, the Tri-Institutional Ph.D. Program in Chemical Biology. and is the Co-Director of the TPCB program.  

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