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How do you make a protein beat, bite, and get beaten up?

Biology Colloquium | Dr. Basudeb Maji | Fri 30th Sep, 2022

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Individual human cells are densely populated with millions of protein molecules. Each of them is born with a cause and dies for a reason. Importantly, such a protein societal network is tightly regulated at multiple and molecular levels. Some control other fellow proteins, some regulate another biomolecule and some self-control. Such interactions happen through precise recognition of each other through molecular interactions. We try to understand how tagging proteins with absolutely new recognition domains interplays in their interactome network and functionality.



Basudeb Maji is an Assistant Professor of Biology at Trivedi School of Biosciences, Ashoka University. He is also an adjunct faculty at the Department of Chemistry. Basudeb earned his Ph.D. from the Indian Institute of Science, Bengaluru and subsequently moved to Harvard Medical School and MIT to pursue his postdoctoral research. His research group works on Synthetic Biology and Chemogenetics platform to address various genetic and infectious diseases. His work primarily involves protein engineering and chemical biology methods to understand the cellular mechanism underlying various genetic diseases. His team focuses on translational research like gene therapy, chemopreventive development, and molecular diagnostics.

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