Kavita Agarwal

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Kavita Agarwal

Assistant Professor of Biology, Ashoka University
DBT-Ramalingaswami Fellow

Ph.D. National Institute of Immunology, New Delhi.
kavita.agarwal@ashoka.edu.in

Kavita Agarwal did her PhD in Chemical Glycobiology at the National Institute of Immunology (New Delhi, India). Subsequently, she completed her postdoctoral training at the Centre for Women’s Infectious Disease Research (cWIDR) and the Department of Molecular Microbiology at Washington University in St. Louis (Missouri, USA). Thereafter, she worked as a Research Associate at the Glycobiology Research & Training Center (GRTC) and the Department of Ob/Gyn and Reproductive Sciences at the University of California San Diego (California, USA). 

Her lab investigates the glycobiology of infectious diseases, with a focus on women’s reproductive health-related complications that are associated with microbial dysbiosis in the vagina. She employs various biochemical, cell biology, and microbiology tools to investigate how members of dysbiotic microbial communities interact with host glycans (carbohydrates decorating mammalian cell surface) and understand the molecular mechanisms that underlie vaginal dysbiosis.

  • Agarwal, K., Choudhury, B., Robinson, L.S., Morrill, S.R., Bouchibiti, Y., Fuentes, D.C., Rosenthal, S.B., Fisch, K.M., Peipert, J.F., Lebrilla, C.B., Allworth, J.E., Lewis, A.L., Lewis, W.G. (2023). Resident microbes shape the vaginal epithelial glycan landscape. Science Translational Medicine, 724, doi: 10.1126/scitranslmed.abp959.
  • Morrill, S.R., Agarwal, K., Saha, S., Lewis, W.G., Gilbert, N.M., Lewis, A.L. (2022). Models of murine vaginal colonization by anaerobically grown bacteria. Journal of Visualized Experiments, 183, e64032, doi:10.3791/64032.
  • Agarwal, K., Lewis, A.L. (2021). Vaginal sialoglycan foraging by Gardnerella vaginalis: Mucus barriers as a meal for unwelcome guests? Glycobiology, doi: 10.1093/glycob/cwab024.
  • Wang, S.-S., Solar, V., Yu, X, Antonopoulos, A., Friedman, A.E., Agarwal, K., Garg, M., Ahmed, S.M., Addhya, A., Nasirikenari, M., Lau, J.T., Dell, A., Haslam, S.M., Sampathkumar, S.-G., Neelamegham, S. (2021). Efficient inhibition of O-glycan biosynthesis using the hexosamine analog Ac5 Cell Chemical Biology, 28, 699-710.
  • Agarwal, K., Robinson, L.S., Foster, L., Lin, H., Tortelli, B., Reno, H., Gilbert, N., Lewis, W.G., Lewis, A.L. (2020). Glycan cross-feeding supports mutualism between Fusobacterium and the vaginal microbiota. PLoS Biology, doi: 10.1371/journal.pbio.3000788.
  • O’Brien, V. P., Gilbert, N., Lebratti, T., Agarwal, K., Foster, L., Shin, H., Lewis, A.L. (2019). Low-dose inoculation of Escherichia coli achieves robust vaginal colonization and results in ascending infection accompanied by severe uterine inflammation in mice. PLoS One, doi: 10.1371/journal.pone.0219941.
  • Dwivedi, V., Saini, P., Tasneem, A., Agarwal, K., Sampathkumar, S.-G. (2018). Differential inhibition of mucin-type O-glycosylation (MTOG) induced by peracetyl N-tioglycolyl-D-galactosamine (Ac5GalNTGc) in myeloid cells. Biochemical and Biophysical Research Communications, 506, 60-65.
  • Lewis, A.L., Robinson, L.S., Agarwal, K., Lewis, W.G. (2016). Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium. Glycobiology, 26, 1107-1119.
  • Agarwal, K., Kaul, R., Garg, M., Asif, S., Jha, S.K., Sampathkumar, S.-G. (2013). Inhibition of mucin-type O-glycosylation through metabolic processing and incorporation of N-thioglycolyl-D-galactosamine peracetate (Ac5GalNTGc). Journal of the American Chemical Society, 135, 14189-14197.
  • Gupta, M.G., Agarwal, K., Prakash, N., Singh D.B. and Mishra, K. (2012). Prediction of miRNA in HIV-1 genome and its targets through artificial neural network: a bioinformatics approach. Network Modeling Analysis in Health Informatics and Bioinformatics, 1, 141-151.

Agarwal Lab is looking for enthusiastic and dedicated scientists to join the laboratory. Students with an interest in glycobiology, cell biology, and host-microbiota interactions may contact Dr. Agarwal with their CV and cover letter.

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