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Other links:
Assistant Professor (Research) and NMR Faculty Incharge, Trivedi School of Bioscience, Ashoka University
PhD from the University of Texas at Dallas
Postdoctoral work at the Wexner Medical Center at Ohio State University
Dr. Niyati Jain is an Assistant Professor at Trivedi School of Biosciences, Ashoka University.
Dr. Jain’s research centers on RNA structural biology, using solution-state NMR spectroscopy to understand how RNA structure and dynamics shape biological function. Her group studies functional non-coding RNAs and regulatory RNA elements, and how these molecules recognize proteins and small-molecule ligands combining NMR with RNA biochemistry, molecular biology, and biophysical approaches.
• Ajit kumar, Purba Daripa, Souvik Maiti, Niyati jain*. Biochemistry 2023 62 (13), 2041-2054 Interaction of hnRNPB1 with Helix-12 of hHOTAIR Reveals the Distinctive Mode of RNA Recognition That Enables the Structural Rearrangement by LCD.
Selected among best papers for 2023 by ACS and also asked to nominate the first Author for Gordon Hannes Scholar.
• Nidhi Katyal, Shantanu Khatri, Ajit Kumar, Akanksha Arun, Purba Daripa, Saman Fatihi, Suresh Kumar, Niyati Jain, Lipi Thukral Autophagy, 2023 (12):3201-3220 AI-based AlphaFold2 significantly expands the structural space of the autophagy pathway.
• Ajit Kumar, Purba Daripa, Kaiser Rasool, Debojyoti Chakraborty, Niyati jain*, and Souvik Maiti* Deciphering the Thermodynamic Landscape of CRISPR/Cas9: Insights into Enhancing Gene Editing Precision and Efficiency J. Phys. Chem. B 2024, 128, 35, 8409–8422.
• Isha Rakheja, Vishal Bharti, S Sahana, Prosad Kumar Das, Gyan Ranjan, Ajit Kumar, Niyati Jain,
Souvik Maiti. Biochemistry 2024 64 (1), 250–265 Development of an In Silico Platform (TRIPinRNA) for the Identification of Novel RNA Intramolecular Triple Helices and Their Validation Using Biophysical Techniques.
• Ajit Kumar#, Purba Daripa#, Srinivas Penumutchu, Souvik Maiti and Niyati jain*. IJBIOMAC Volume 312, June 2025, 144210 “Thermodynamic Insights into N6 Methyladenosine-Modified Ribonucleic Acids and Their Interactions with the RNA Recognition Motif of Heterogeneous Nuclear Ribonucleoprotein C”.
• Shalini Mishra#, Ajit Kumar#, Priyanka Kumari, Kaiser Rasool, Souvik Maiti and Niyati jain*. Biochemistry 64 (16), 3535-3548 2025/7/30. “Thermodynamics and Binding Mechanism of Insulin-like Growth Factor Binding Protein 1 (IGF2BP1) and Y3 RNA Interaction: Exploring the Mode and Mechanism of Their Interaction.”
• Ajit Kumar, Srinivasa Penumutchu, Love Panchariya, Priyanka Kumari, Shubham Thakur, Purba Daripa, Vandana Singh, Arockiasamy Arulandu, Souvik Maiti, Mandar V Deshmukh, Niyati jain*.” Loop of fate: structural and mechanistic insights into hnRNPA1 binding to the hepatitis C virus RNA.” 2026/2/1 RNA 32 (2), 215-236.
• Deepanshi Gahlot, Jesu Castin, Shruti Mathur, Debajyoti Das, Ajit Kumar, Akanksha Arun, Chandrima Gain, Mridul Sharma, Ravi Kant Pal, Niyati Jain, Bichitra K Biswal, Rajat Singh, Lipi Thukral “A novel lipid-triggered allosteric site modulates LC3-LIR receptor binding activity” Nature communication accepted 2026
• Ajit Kumar, Shubham thakur, Priyanka kumari, Shalini Mishra, Souvik Maiti, and Niyati jain*.
Engineered FnCas9 and their affinity and specificity to different PAM targets. Biochemistry ACS accepted 2026
• Ramalingaswami Fellowship (2018–2019) Department of Biotechnology, Ministry of Science and Technology, Government of India
• DST Young Scientist Fast Track Grant (2012) Ministry of Science and Technology, New Delhi, India
• Graduate Student Scholarship (2006–2010)University of Texas at Dallas
• Travel Award – Biocat Advanced SAXS Training Course (Oct 2015)User at Advanced Photon Source, Argonne National Laboratory, USA
• Travel Grant – CRNA Workshop “Introduction to X-ray Crystallography”Ann Arbor, Michigan, March 26–27, 2014
