Shraddha Karve

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Ashoka University

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Shraddha Karve

Assistant Professor of Research at Koita Centre for Digital Health, Ashoka University

Ph.D. IISER, Pune
https://sites.google.com/view/shraddha-karve-lab/home shraddha.karve@ashoka.edu.in

Shraddha Karve was earlier working at Ashoka as a Faculty Fellow.  She was a Postdoctoral Fellow for 4 years at the University of Zurich in Switzerland.

She obtained her Master of Science (Microbiology) from Pune University, after which she got her doctoral degree from the Indian Institute of Science Education and Research, Pune. Currently at Ashoka, she and her group study antimicrobial resistance in tertiary healthcare centers using genomic approaches and the evolution of de novo resistance using laboratory evolution experiments. In 2020, Shraddha received the Indian National Science Academy (INSA) Young Scientist’s Award.

  • Gheewalla, V. Karthikeyan, Y. Jadhav, K. Kulkarni, A. Tyagi, J. Jagannadham, S. Budhiraja, B. Tarai, M. Kavathekar, S. Karve. Genomic Landscape of Antimicrobial Resistance in India: Findings from a Multi-Species Surveillance Study. In review.
  • Gheewalla, Y. Jadhav, J. Jagannadham, A. Tyagi, S. Budhiraja, B. Tarai & S. Karve. Genomic insights into six clinical isolates of Stenotrophomonas maltophilia from Northern India. bioRxiv.
  • Karve. Evolutionary novelties in bacteria and the missing backdrop of the environment. Opinion article submitted to Environmental Microbiology. 27.1 (2025):e70044.
  • Patil, A. Siji, D. Mallur, N. Gheewalla, S.Karve, M. Kavathekar, B. Tarai, M. Naik, B. S. Kruthika, V. Hegde, J. Rangineni, V. Gupta, V. Chandru, B. E. Pradeep, R. Arora. PathCrisp: An Innovative Molecular Diagnostic Tool for Early Detection of NDM-Resistant Infections. Scientific Reports. 15.1(2025):490.
  • Gheewalla, J. Jagannadham, R. Kutum & S. Karve. India needs more whole-genome sequencing of diverse priority pathogens for effective study and surveillance of antimicrobial resistance. bioRxiv.
  • Karve* & A. Wagner. Environmental complexity is more important than mutation in driving the evolution of latent novel traits in E. coli. Nature communications 13.1 (2022): 1-12. (* co-corresponding author)
  • Karve, P. Dasmeh, J. Zheng & A. Wagner. Low protein expression enhances phenotypic evolvability by intensifying selection on folding stability. Nature Ecology & Evolution 6.8 (2022): 1155-1164.
  • Karve* & A. Wagner. 2022. Multiple novel traits originate non-adaptively in bacteria evolving on single antibiotics. Molecular Biology and Evolution, 39(1):msab341. (* co-corresponding author)
  • Chavhan, S. Karve., & S. Dey. 2019. Adapting in larger numbers can increase the vulnerability of Escherichia coli populations to environmental changes. Evolution, 73: 836-846.
  • Karve, D. Bhave, and S. Dey. 2018. Extent of adaptation is not limited by unpredictability of the environment in laboratory populations of Escherichia coli. Journal of Evolutionary Biology 31: 1420-1426.
  • Karve, D. Bhave, D. Nevgi, and S. Dey. 2016. Escherichia coli populations adapt to complex, unpredictable fluctuations by minimizing trade-offs across environments. Journal of Evolutionary Biology 29: 2545-2555.
  • Karve and M. Mangalam. 2016. Junior researchers: Hasty publication compromises rigour. Nature 531:305.
  • Karve, K. Tiwary, S Selveshwari & S.Dey. 2016. Environmental fluctuations do not select for increased variation or population-based resistance in Escherichia coli. Journal of Biosciences 41(1):39-49.
  • Karve, S. Daniel, Y. D. Chavhan, A. Anand, S.S.Kharola & S. Dey. 2015. Escherichia coli populations in unpredictably fluctuating environments evolve to face novel stresses through enhanced efflux activity. Journal of Evolutionary Biology 28: 1131-1143.
  • Mangalam and S. Karve. 2015. Comment on “Number-space mapping in the newborn chick resembles humans’ mental number line”. Science 348: 1438.
  • Karve, K. Shurpali, N. Dahanukar, S. Paranjape, M. Jog, P. Belsare, M. Watve. 2011. Money handling and obesity: A test of exaptation hypothesis. Current Science 100: 1695-1700.

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