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Centre for Bioinformatics & Computational Biology

The Centre for Bioinformatics and Computational Biology at Ashoka University will study biological processes through advanced mathematical and computational modelling. The centre concentrates on interdisciplinary approaches that combine chemistry, physics and biology together with mathematics, information science and computer science. The centre is actively engaged in the analysis of a diverse set of genomic, sequence, and proteomics data. It offers both internship programs and hands-on training to prepare new generations of students in modern methods of bioinformatics and computational biology. The Centre may explore offering a major and a minor in computational biology to undergraduate students.

Vision

Our vision is to provide a platform for research and training in computational biology through 

  • Knowledge discovery and transfer
  • Vocational training and education
  • Industrial collaborations
  • Scientific knowledge dissemination

Theme of the Centre

Understanding different biological problems will require finding patterns in large sets of diverse data. The centre will study a range of  biological problems at the systems levels using AI and ML methods as well as mathematical  modelling. Many different types of data will be integrated together, including genome sequences, transcriptomic, metabolomics, proteomics outputs, digital images, disease spread statistics etc. 

The main focus of the Centre will be in the core area of application of computational and mathematical principles and methods to solve biological problems. The Centre will develop techniques that will reduce the need for large computing resources through the use of novel and fast algorithms. 

Objective

  • Research in the area of computational genomics, computational biology and modelling of biological systems and artificial intelligence in biology and medicine
  • Initiate masters and Ph.D. level programs in these areas.
  • Offer workshops, training, internship and visiting programs for students and faculty from outside the University.

Support and Collaborations

Projects

  1. Computational Systems Biology
  2. Mathematical Models
  3. Metagenomics
  4. Simulation Model
  5. Cancer Transcriptome
  6. Microbial Pathogenicity Studies
  7. Rare Diseases
  8. Image Processing
  9. Single-cell studies
  10. Structural Biology

Publications

  • Mozaffer, Farhina, Philip Cherian, Sandeep Krishna, Brian Wahl, and Gautam I. Menon. “Effect of hybrid immunity, school reopening, and the Omicron variant on the trajectory of the COVID-19 epidemic in India: a modeling study.” The Lancet Regional Health-Southeast Asia 8 (2023): 100095.
  • Maiya, Reshma, Swagata Dey, Krishanu Ray, and Gautam I. Menon. “The interplay of active and passive mechanisms in slow axonal transport.” Biophysical Journal 122, no. 2 (2023): 333-345.
  • Jaiswal, Sarika, Bharti Aneja, Jaisri Jagannadham, Bharati Pandey, Rajender Singh Chhokar, Subhash Chander Gill, Om Parkash Ahlawat et al. “Unveiling the Wheat Microbiome under Varied Agricultural Field Conditions.” Microbiology Spectrum 10, no. 6 (2022): e02633-22.
Study at Ashoka

Study at Ashoka